POSTED: 26th May 2009

Visiting Fellowship and PhD student positions available through the Saskatoon Research Centre – Agriculture and Agri-Food Canada
Training Opportunities in Trichome Functional Genomics (a PhD graduate student and a Visiting Fellow): Tenure is at the Saskatoon Research Centre and University of Saskatchewan.


Research Projects: The aim and responsibilities are to conduct research to understand trichome (hair) development in Brassica plant species and to apply Arabidopsis and Brassica genes to enhance the Brassica napus and Brassica carinata trichome systems in support of the development of “Hairy Canola” and “Hairy Ethiopian Mustard” germplasm with resistance to the crucifer flea beetle. Current projects include the study of trichome (hair) regulation in Brassica napus, moving the “hairy canola” trait into new Brassica napus and Brassica carinata germplasm, determining Arabidopsis genes and promoters that can stimulate trichome density and branching in Brassica napus, and finding characterizing novel trichome mutations and genes from an Arabidopsis activation-tagged population.
Background: Flea beetles (Phyllotreta cruciferae) are the most damaging insect pest for canola on the prairies. Farmers are desperate for help with this pest, since some of the best chemical protection has been deregistered and 20 years of traditional plant selection has been unsuccessful at developing flea beetle resistant canola. A few years ago, 2 trichome regulatory genes from Arabidopsis were introduced into canola and stimulated 1000-fold higher trichome density on canola seedling leaves and stems. [Gruber, M.Y., Wang, S., Ethier, S., Holowachuk, J., Bonham-Smith, P.C., Soroka, J., Lloyd, A. 2006. “HAIRY CANOLA” – Arabidopsis GL3 induces a dense covering of trichomes on Brassica napus seedlings. Plant Mol Biol 60: 679-698]. This trait shows strong resistance to flea beetles (Report to The Canola Council, 2008), but additional basic and applied science is required to see this trait turn into breeding germplasm.hn

Successful candidates will join a Saskatoon Research Centre lab which includes 4 Visiting Fellows, two technicians and 4 PhD students headed by Dr. Margaret Gruber (SRC Genomics). Trichome research projects are conducted collaboratively with Dr. Isobel Parkin (SRC Genomics), Dr. Julie Soroka (SRC Entomology), Dr. Kevin Falk and Dr. Gerhard Rakow (SRC Plant Breeding), Dr. Peta Bonham-Smith, Biology Dept., Univ. of Saskatchewan, and Dr. Sharon Regan, Biology Dept., Queen’s University. The project could involve collaboration with Dr. Martin Hulskamp at The University of Koln, Germany. Research training could include molecular and expression analysis, including microarrays, ESTs, qRT-PCR, RNAi knockdown and over-expression in transgenic model plants and crop plants, recombinant protein isolation, enzyme assays, functional characterization of activation-tagged mutants, bioinformatics, and phytochemical analysis (HPLC-UV/MS-MS, GC-MS, or UPLC-TQD).

Facilities: The Saskatoon Research Centre is a well-funded facility with analytical chemistry, genomics and biochemistry facilities. Researchers at the Centre have access to basic research labs through to applied research and crop evaluation labs in a pleasant, modern setting that includes 3 research farms and several GMO crop evaluation sites. “Hairy Canola” projects are linked into national Canadian agricultural research priorities. Saskatoon is the centre for Brassica crop genomics research in Canada. Other projects in the lab focus on the functional genomics of proanthocyanidin and carotenoid accumulation, saline and low fertility stress, biorefinery concepts, and ruminant nutritional and feed structure characteristics. The lab is a member of the ABIP-funded Canadian Cellulosic Biofuel Network. SRC enjoys a strong relationship with genomics and analytical chemistry groups and the DNA Analysis Lab at the Plant Biotechnology Institute, NRC Saskatoon, and accesses analytical chemistry facilities (NMR, ICMS) and microscopy facilities at the University of Saskatchewan Structural Sciences Centre, Geology Dept., the Biology Microscopy Centre and the Canadian Light Source (Synchrotron) as needed.

Applicants for PhD graduate studies should submit TWO applications below:

1st - to graduate studies at the University of Saskatchewan and

2nd - to the Research Affiliate Programme of Agriculture and Agri-Food Canada

University of Saskatchewan Graduate Study applications should include a curriculum vita, skills and publication lists, copies of university transcripts, any other relevant documentation (eg. visa documents, birth certificate), and an application letter outlining research interests to Dr. Peta Bonham Smith (below), with a copy to Dr. M. Gruber (above). The letter should also include an explanation for the application to the Department of Biology and how previous experience will contribute to the position. Applications should be submitted by June 30, 2009 (to be evaluated for a Sept. 1, 2009 start date).

Dr. Peta Bonham Smith,
Head, Dept. of Biology,
University of Saskatchewan,
W.P. Thompson Building
112 Science Place,
Saskatoon, Saskatchewan,
Canada S7N5E2
Phone: 1-306-966-4400 (office); 1-306- 966-4430 (lab)
FAX: 1-306-966-4461
Email: peta.bonhams@usask.ca
http://homepage.usask.ca/~pcb512/index.html
http://www.usask.ca/biology/home/gradform.html
http://www.usask.ca/biology.


Visiting Fellowship Candidates should submit their application to Ms. Lilianne Cousineau at Agriculture and Agri-Food Canada (Office for NSERC Visiting Fellowship to a Canadian Government Laboratory) and on the NSERC website for evaluation (preferred start date July 1, 2009). The application and documentation is found at the NSERC website “http://www.nserc-crsng.gc.ca/Students-Etudiants/PD-NP/Laboratories Laboratoires/index_eng .asp”. Interested candidates should also forward their CV, skills and publications lists, and 3 references (with email addresses) to:

Dr. Margaret Y. Gruber,
Molecular Genetics and Genomics,
Saskatoon Research Centre,
Agriculture and Agri-Food Canada,
105 Science Cresc.,
Saskatoon, Saskatchewan,
Canada S7N0X2
Phone: 1-306-956-7263 (office); 1-306-956-7295 (lab)
FAX: 1-306-956-7247
Email: Margie.Gruber@agr.gc.ca, and gruberkm@sasktel.net


2nd: Research Affiliate Programme Award Qualifications and Application Process: General information and requirements for the Research Affiliate Program and applications can be viewed on the Research Affiliate Program website for the Government of Canada: http://jobs-emplois.gc.ca/rap-par/index-eng.htm. The specific job posting for “Graduate Assistant - PhD Student (Trichomes)” at the Saskatoon Research Centre of Agriculture and Agri-Food Canada will appear under “Current Opportunities” on the RAP website. Applications for the RAP program must be submitted on-line through the RAP posting. Candidates must show evidence of acceptance into a full-time PhD programme at the Dept. of Biology, University of Saskatchewan before the award is given.