Modules 7 and 8
Rota and Coronaviruses
(bovine rota and coronaviruses, feline enteric coronavirus and infectious peritonitis, SARS virus)

The entric rota and corona viruses cause similar diarrhea-causing illness in young animals. In addition, the coronaviruses are also associated with respiratory disease. The feline enteric coronavirus is interesting in that while it is widespread in cats and usually causes mild disease it can change to a virulent form with leads to infectious peritonitis, a fatal disease, in some cats.

Another interesting coronavirus appeared on the scene a few years ago causing death as well as enormous economic loss. The virus that caused severe acute respiratory syndrome (SARS) maintained in animal reservoirs in China and south-east Asia but its introduction into humans can lead to fatal disease.

Learning objectives (What you should be able to do at the end of the module):

1. Know
•    The main viral causes of diarrhoea in new-born animals

2. Explain
•    Main properties of rota and coronaviruses
•    Why infection with these viruses leads to diarrhoea
•    How rota and coronaviruses are detected
•    How diarrhoea in newborn animals can be prevented (or incidence reduced)
•    What is FIP
•    How the  FIP virus is related to the ubiquitous feline enteric coronavirus
•    Pathogenesis of FIP
•    How is FIP diagnosed
•    Can FIP be prevented?
•    Factors that may have led to the 2003 SARS pandemic


  1. Viral causes of diarrhoea in neonates
  2. Rotaviruses
  3. Coronaviruses
  4. SARS an emerging/emerged/extinguished (?) zoonotic dsease


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