BHV-1 and BVDV:
Clinical Disease and Vaccination




Cemaine Tsang & Ashley Begg
Western College of Veterinary Medicine


Bovine herpesvirus-1 (BHV-1) and bovine viral diarrhea virus (BVDV) have major econimic implications in cattle production today. These two viruses share the unique ability to cross the placenta of epitheliochoral species and infect the fetus in utero. Fetal infection can lead to many manifestations however it commonly results in economic loss through abortion or persistent infection. Details of viral characteristics and clinical disease of BHV-1 and BVDV are presented to help better understand the complexity and variability of these viruses and their diseases. Vaccination is a common method for control of BHV-1 and BVDV infection however vaccine efficacy is a constant concern. This is explored with respect to current vaccination protocols and immunity in BHV-1 infection and is also addressed in new experimental vaccination design currently occuring  for BVDV infection and disease.


Bovine Herpsevirus-1
Viral Characteristics    Clinical Disease    Vaccination


Bovine Viral Diarrhea Virus
Viral Characteristics    Clinical Disease    Vaccination


What the future holds for BHV-1 and BVDV control


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