Cerebellar hypoplasia - deficiency of cells of the cerebellum, the degree and distribution of which is variable. (1)
Core vaccine - a vaccine that should be included in an animal's vaccination program to prevent disease from a high risk virus.
ELISA (enzyme-linked immunosorbant assay) - a type of test used to detect and measure either antigen of a virus or antibody produced to a virus. The antigen or antibody is bound to a solid substance (polystyrene surface), and a second antibody to which enzyme is conjugated is added, followed by a substrate for the enzyme. Positive results are indicated by a colour change. (1)
Histology - section of anatomy dealing with microscopic structure, composition and function of tissues. (1)
Immunofluorescence - a method of determining the location of antigen (or antibody) in a tissue section or smear using a specific antibody (or antigen) labeled with a fluorochrome. (1)
Lameness - incapable of normal locomotion; deviation from the normal gait. (1)
Macrophages - large, mononuclear, highly phagocytic cells derived from bone marrow that participate in the 'cleaning-up' of cellular debris and infections within a tissue. (1)
Non-core vaccine - a vaccine that is not normally included in an animal's vaccination program, unless there is high risk for infection.
PCR (polymerase chain reaction) - a method by which a specific sequence of DNA is amplified exponentially to a concentration that is detectable by various lab techniques. (1)
Vaccine - a suspension of attenuated or killed microorganisms (viruses, bacteria or rickettsiae), administered for prevention, amelioration or treatment of infectious diseases. (1)
- Attenuated (modified-live) vaccine - a vaccine prepared from live microorganisms that have lost their virulence but retain their ability to induce protective immmunity. (1)
- Inactivated vaccine - a vaccine prepared from dead microorganisms. (1)
Virulence - the degree of pathogenicity of a microorganism as indicated by case fatality rates and/or its ability to invade the tissues of the host. (1)