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Canine Distemper Virus
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Glossary
Ailuronidae
the family of pandas.
Alopecia
deficiency of the hair coat.
Anorexia
lack or loss of appetite for food.
Ante mortem
performed or occurring before death.
Antibiotics
a chemical substance produced by a microorganism that has the capacity, in dilute solutions, to kill or inhibit the growth of other microorganisms.
Astrocyte a neuroglial cell of ectodermal origin, characterized by fibrous or protoplasmic processes; collectively called astroglia or macroglia.
Ataxia failure of muscular coordination; irregularity of muscular action.
Bronchitis inflammation of one or more bronchi.
Bronchopneumonia inflammation of the bronchi and lungs, usually beginning in the terminal bronchioles.
Carrier animal an animal which harbors a disease organism in its body without manifest signs, thus acting as a carrier or distributor of infection.
Catarrhal  enteritis inflammation of the intestinal mucosa with free discharge, resulting in clinical signs of diarrhea, sometimes  dysentery, abdominal pain and dehydration and electrolyte loss and imbalance.
Chorioretinitis inflammation of the choroid and retina of the eye.
Civet a large cat-like animal but with short legs and a long muzzle and without retractile claws.
Colostrum the thick secretion present in the mammary gland in increasing amounts for several days or weeks, depending on the species, before and for about a week after parturition.  It is very rich in maternal antibodies and is essential in providing passive immunity to the neonate.
Conjunctivitis inflammation of the conjunctiva.
CSF (cerebrospinal fluid) Fluid within the central canal of the spinal cord, and the four ventricles of the brain.
Cystitis inflammation of the urinary bladder.
Demyelination destruction, removal, or loss of the myelin sheath of a nerve or nerves.
Dermatitis inflammation of the skin.
Dyspnea labored or difficult breathing.
ELISA (Enzyme-Linked Immunosorbent Assay) A type of primary binding test used to detect and measure either antigen or antibody.
Encephalitis inflammation of the brain.
Endemic present in a predictable, continuous pattern in an animal community at all times; said of a disease which is clustered in space but not in time.
Erythema redness of the skin caused by congestion of the capillaries in the lower layers of the skin.  It occurs wiht any skin injury, infection or inflammation.
Felidae the family of cats; includes the domestic cat and feral (untamed/wild) cats of approximately the same dimensions.
Fomite an inanimate object or material in which disease-producing agents may be conveyed, e.g. feces, bedding, buckets, boots.
Glial cells
neuroglia, the supporting cells of the central nervous system, made up of astrocytes, oligodendrocytes and microglia.
Glucocorticosteroids any corticoid substance that increases gluconeogenesis, raising the concentration of liver glycogen and blood sugar.  Widely used as anti-inflammatory agents.
Hyaenidae the family of hyenas.
Hyperkeratosis increased thickness of the keratinized epidermis.
Hypoglobulinemia lower than normal levels of globulin (a protein) in the blood.
Immunoflourescence a method of determining the location of antigen (or antibody) in a tissue section or smear using a specific antibody (or antigen) labeled with a fluorochrome.
Immunoperoxidase test a technique of histological staining that provides morphological details and immunological identification.
Inclusion bodies round, oval or irregular-shaped bodies in the cytoplasm and nucleus of cells, as in diseases due to viral infection, such as rabies, inclusion body rhinitis.
Interstitial pneumonia pneumonia in which there is diffuse or patchy damage to alveolar septa widely distributed through the lungs.
Intussussception prolapse of one part of the intestine into the lumen of an immediately adjacent part, causing intestinal obstruction.
Jaundice yellowness of skin, sclerae, mucous membranes, and excretions due to hyperbilirubinemia and deposition of bile pigments.
Keratinocyte the cell of the epidermis that synthesizes keratin.
Leukopenia reduction in the number of leukocytes in the blood.
Maternal antibodies antibodies passively transferred from dam to fetus or neonate, transplacentally or via colostrum or yok sac.
Meningoencephalitis inflammation of the brain and its meninges.
Modified Live Virus vaccine a vaccine prepared from live microorganisms that have lost their virulence but retained their ability to induce protective immunity.
Mononuclear cells having only one nucleus.  The mononuclear phagocytes are the macrophages.
Morbillivirus one of the three genera of viruses in the family Paramyxoviridae.  It includes canine distemper.
Mortality
death as a statistic (death rate).
Mustelidae a family of carnivores, both aquatic and terrestrial, an almost 70 species; includes the ferret, mink, skunk, sea otter and weasel (among others).
Myoclonus repetitive, rhythmic contractions of a group of skeletal muscles, persisting in sleep.
Natural infection infection by 'normal' means, as would occur in nature, without the intervention of humans.
Neuritis inflammation of a nerve.
Neuropathy a general term denoting functional disturbances and pathological changes in the peripheral nervous system.
Neutralizing antibody one that reduces, destroys or blocks infectivity of an infectious agent, particularly virus, by partial or complete destruction of the agent.
Oligodendrocytes non-neural cells, forming part of the adventitial structure of the central nervous system.
Paramyxoviridae a family of viruses in the order Mononegavirales containing three genera; Parainfluenzavirus, Morbillivirus and Pneumovirus.
Paresis slight or incomplete paralysis.
Pathognomonic specifically distinctive or characteristic of a disease or pathological condition.
Planum nasale the space between the nostrils.
Polioencephalomalacia softening of the cerebrocortical gray matter distributed in a laminar pattern.
Post mortem performed or occurring after death.
Procyonidae a family of animals comprising the ring-tailed cat, cacomistle, raccoon, coatimundi, mountain coati, kinkajou, olingo, lesser panda and giant panda.
Pruritus itching; common in many types of skin disorders.
Pustule a small, elevated, circumscribed, pus-containing lesion of the skin or cornea; usually thin-walled and ruptures easily.
Pyuria pus in the urine.
Reservoir an alternative host or passive carrier of a pathogenic organism.
Rhinitis inflammation of the mucous membrane of the nose.
RT-PCR (Reverse Transcriptase Polymerase Chain Reaction) A reaction applied when the target sequence in RNA, such as viral RNA or messenger RNA.
Seroneutralization assay determination of the amount or activity of any particular constituent (i.e. antibody) in serum.
Single stranded negative sense RNA virus a virus whose genome is made up of an unpaired strand and is composed of RNA which is of opposite polarity to messenger RNA so that it must first be transcribed to produce messenger RNA.
Strain one or more organisms within a species or variety, characterized by some particular quality.
Susceptibility test an in vitro test of the effectiveness of selected antibacterial agents against bacteria recovered from a patient.
Tenesmus ineffectual and painful straining at defacation or in urinating.
Ursidae
family of bears
Vaccination the introduction of vaccine into the body to produce immunity to a specific disease.
Viremia the presence of viruses in the blood either as free virus or a cell associated viremia.
Virulence the competence of any infectious agent to produce pathological effects.
Viverridae the family of civets, genets, and mongoose.