Animal Diseases

All TSEs are progressive and ultimately fatal diseases. All of the animal TSEs, with the exception of Scrapie and CWD, can only be diagnosed definitively on necropsy. Scrapie and CWD can be diagnosed via a biopsy of the tonsil or conjunctiva and then performing PrP immunohistochemistry. A negative result, however, does not mean that the animal is free of the disease(18).

                        Prions are considered the causative agent for a number of animal diseases:

                        Bovine Spongiform Encephalopathy
                        Chronic Wasting Disease
                        Other:  Transmissible Mink Encephalopathy
                                    Feline Spongiform Encephalopathy
                                    Exotic Ungulate Encephalopathy   

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