Post
mortem
Necropsy:
(source 1)
·
Lungs:
o
Large,
heavy (2-3x normal weight) +/- rib
impressions
(source
7).
o
Firm,
do not collapse and are gray-blue or gray-yellow in all lobes
o
Evidence
of secondary bacterial pneumonia may be seen
(source 7).
·
Lymph nodes:
o
Tracheobronchial
and mediastinal lymphnodes are greatly enlarged, bulge on cut surface,
and may
appear gray-white.
·
Joints:
o
Arthritis
commonly affects the appendicular joints.
o
Extensive
synovial proliferation, fibrosis of the joint capsule, and degeneration
of the
articular cartilage and bone.
·
Central
nervous system:
o
Gross
examination of the brain and spinal cord is normal
Histology: (source 1)
·
Lungs:
o
Chronic
diffuse interstitial pneumonia, with a complete absence of healing
suggesting that the
disease is progressive and never reaches a healing stage.
o
Hyperplasia
of lymphoid cells around airways and blood vessels.
o
Accumulation
of mononuclear cells in the interstitium.
(source 7).
·
Central
Nervous System:
o
Lymphocytic
meningitis
o
Choroiditis
o
Leukoencephalitis