Clinical Signs
Order of occurrence:
  • Most commonly, the first signs are increased salivation and drooling
  • Mild increase in body temperature (fever)
    • Occurs immediately prior to or at the same time as lesions develop
  • Formation of blister-like lesions on the upper surface of tongue, inner surface of lips, gums, nostrils and/or angles of mouth
      • Lesions on the coronary bands can lead to lameness
  • Blister-like lesions break open causing ulcers to develop
  • Horses will profusely drool/salivate/froth from the mouth
    • CAREFUL- this sign can be mistaken for biting problems, dental abnormalities or colic
  • Horses will go off feed and water due to the pain from ulceration
    • Results in mild to significant weight loss
May also see crusting lesions of the muzzle, ventral abdomen, sheath, and udder
Horses are more severely affected than other species affect by Vesicular Stomatitis