Clinical Signs

Feline Panleukopenia virus has similar clinical sings to those of canine parvovirus 2.  The most common signs cats present with are:
-Acute Fever (40-41 °C)
-Diarrhea
-Depression
-Anorexia
-Vomiting (Billious)
-Severe dehydration
-Seizures

Exam Findings and Diagnosis


In addition to the common clinical signs listed above owners may report that their cats began vomiting a few days after the onset of fever. Cats have also been reported to hang their heads above their water bowl but not drink. Complications that can arise from infection include abortions if a cat is infected during the first trimester of pregnancy. If cats are infected later in pregnancy the virus can lead to cerebellar hypoplasia in kittens.

Physical Exam Findings: In addition to the presenting signs physical exam often reveals: skin tenting due to severe dehydration, abdominal pain, and swollen abdominal lymph nodes. In kittens infected in utero signs include retinal lesions, which appear as distinct grey areas in the eye, and ataxia and tremors associated with cerebellar hypoplasia.

Blood Work: A complete blood count (CBC) lymphopenia, severe (pan) leukopenia, and thrombocytopenia. Panleukopenia is define as a white blood cell count between 50-3000 WBC/µL. In cases with a count < 2000 WBC/µL a poor prognosis is given. 

Diagnostic Tests: The canine-parvo virus ELISA snap test is the most commonly used in practice to detect  FPV during the acute phase of infection. Panleukopenia on the CBC and a postive ELISA test results are combined to give a diagnosis of FPV. Cats can be positive for this test if they were vaccinated for FPV within 5-12 days of the test. Other diagnostic tests availabe include virus isolation, PCR, and antibody titre tests.


Video

A Kitten with cerebellar hypoplasiacerebellar


http://www.youtube.com/watch?v=xLlL24shW7E&feature=related