Treatment:
-    At present there is no known cure for FIP. Although spontaneous remissions have been documented in treated cats, the mortality rate of cats clinically infected with FIP remains at 95%.
-    Treatment is indicated in cats lacking neurological signs, in good physical condition, with a healthy appetite and no concurrent infection.  Current treatment regimes include:
o    Reduction of stress
o    High doses of anti-inflammatory and immunosuppressive drugs to slow the progression of lesions
♣    Prednisolone, Cyclophosphamide, Thalidomide, Thromboxane synthetase inhibitors, Pentoxiphylline, Chlorambucil
o    Supportive care
♣    Blood transfusion, fluid therapy and drainage of accumulating fluids
♣    Antibiotic therapy to prevent concurrent bacterial infection
♣    Proper dietary management
-    An uncontrolled study conducted by Ishida et al. published in 2003, suggested that promise existed in the use of recombinant feline interferon and glucocorticoid in the treatment of FIP. Subsequent randomized, controlled clinical trials have shown no statistical difference between treatment and control groups using the same therapy.
 
-    It is important to recognize that these treatments are palliative and should only be continued as long as the cat  
          enjoys a good quality of life.
Prevention:
-    Vaccination
o    Currently only one vaccine is licensed for prevention of FIP:
o     Primucell®, manufactured by Pfizer, is a modified live, temperature sensitive, intranasal vaccine that has been shown to protect 60-90% of vaccinates.
♣    Vaccinates must be at least 16 weeks old
♣    The vaccine must be given prior to exposure (preferably 4 weeks prior)
♣    Duration of protection is thought to be limited
♣    The vaccine is ineffective in cats already infected with FCoV
♣    2 doses are required three weeks apart
o    Vaccination is likely unwarranted for cats that live primarily/entirely indoors and are unlikely to come into contact with other individuals. However, there is evidence that suggests that the use of Primucell® in shelters and catteries may be beneficial in reducing morbidity/mortality in those facilities with an endemic infection.
-    The major risk of infection with FCoV comes in multiple cat environments such as shelters and catteries (1). In these situations it is important to:
o    Keep littler boxes clean and away from food/water dishes
♣    Clear and clean boxes daily (feces is the primary source if Coronavirus)
♣    Use a “non-tracking” litter
o    Isolate cats that test positive for FCoV antibodies
o    Immunize against other feline viruses
o    Reduce crowding stress
o    Disinfect cages and allow to sit empty if possible
o    Clip hind-end hair on long hair breeds
-    It has been shown that there is a genetic link to the risk of developing FIP and breeding programs should therefore take this into account when selecting which pedigrees to propagate.
-    Prevent FCoV infection in kittens
o    Kittens are protected from infection by maternally derived antibodies (MDA) from an infected queen for approximately 5-6 weeks
o    It is therefore possible to breed uninfected kittens if early weaning protocols are established ensuring the removal of the kittens before MDAs wane
-    Develop a health and hygiene protocol
Zoonotic Potential:
-    Humans cannot become infected with Feline Coronavirus or Feline Infectious Peritonitis.